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NanoBioLife
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  • R&D
  • R&D
  • R&D

    Research and Development

    R&D

    We are always committed to research and development.

    R&D

    Nano Bio Life is based on unsurpassed quantitative analysis technology We focus on R&D to provide a variety of immunodiagnostic and molecular diagnostic devices, cancer diagnostic and microbiological diagnostic solutions.

    • Research Area

    • Rapid Molecular Diagnostics
      Field type rapid molecular diagnostic solution used for diagnostic reagents in various infectious diseases / Completed the task of developing and commercializing a respiratory virus detection system for all ministries
      Immunodiagnostics
      Highly sensitive quantitative immunodiagnostic solution using confocal optical technology / Affordable solution for semi-quantitative immunodiagnostic using optical camera technology
      Cancer Diagnosis
      Blood cancer cell isolation and cell imaging solution
      Microbial Diagnostics
      Microbial point-of-care autofluorescence detection solution
    • Core Technology

      1. 01

        High sensitivity gold/fluorescence quantitation technology using confocal optical technology

        Loop-Mediated Amplification principle

        Sample 1. Positive SARS-CoV-2

        Sample Component Flu. Ct value Result
        Sample 1 N gene FAM ≤ 25 SARS-CoV-2 양성
        RdRP gene Cy5 ≤ 25
        RPLP0 (=HuPO) HEX ≤ 25

        Sample 2. Negative SARS-CoV-2

        Sample Component Flu. Ct value Result
        Sample 2 N gene FAM ≤ 25 SARS-CoV-2 양성
        RdRP gene Cy5 ≤ 25
        RPLP0 (=HuPO) HEX ≤ 25
      2. 02

        Rapid molecular diagnostic technology using isothermal amplification

        High-Speed Confocal Light Detection Technology

        Adopting optical sensor technology with higher sensitivity than conventional camera methods

      3. 03

        Algorithm and Analysis Software Development Technology

        Microarray quantitative analysis SW algorithm

        Microarray quantitative analysis SW algorithm

        Microarray spot analysis algorithm (X*Y:4*3 spot standard)

      4. 04

        Absorption analysis technology using camera optical technology

        NCR-200 commercialization: camera type, multiple, cost-effective LFA color reader

        • CPU: Allwinner V536 CPU (Cortex-a7)
        • DRAM: 2Gbytes
        • LCD: 4inch touch lcd
        • Camera: HD type camera (1920X1080) * Multi model : 2 camera (FHD 2channel)
        • USB Device support
        • Light : high brightness LED Multi model . 6etc)
        • Power 5V USB or Battery (4.7V), Battery: 4000mAh

        Paxgenbio - 14 Line x 8 Kit

        GMDBiotech -22 Line x 6 Kit

      5. 05

        Lateral Flow Microarray (LFMA) Multiple Detection Technology

        Simultaneous multi-biomarker detection technology

        Simultaneous multi-biomarker detection technology

        Characteristics

        Dynamic range of wideband detection of various biomarkers: several pg/ml to several tens of ng/ml
        Securing discontinuous dynamic range with variable output irradiated light and detection gain correction technology
        Noise reduction and optimal quantification algorithm according to multiple detection of biomarkers
        Wide detection range and multi-detection response for biomarkers of various concentrations

        Differentiation

        Multimodal Diagnostic Kit POCT Reader: Multiple biomarkers detected with one device
        Detect kits loaded with biomarkers with various detection concentrations in one system
        Small device, cost-effective and convenient for use
      6. 06

        Diagnostic kit development technology using antigen / antibody reaction

        Clinical Performance

        Total eighty-three of human nasopharyngeal and eight of nasal swab specimens from asymptomatic and symptomatic patients were analyzed.

        Clinical Study I – Nasopharyngeal swab

        Nasopharyngeal swab RT-PCR
        Positive Negative Total
        NanoCare™
        COVID-19 Antigen (Ag) Kit
        Positive 31 - 31
        Negative 2 50 52
        Total 33 50 83
        Positive Percent Agreement (PPA) 93.94% (31/33)
        Negative Percent Agreement (NPA) 100% (50/50)

        Clinical Study II – Nasal swab

        Nasal swa RT-PCR
        Positive Negative Total
        NanoCare™
        COVID-19 Antigen (Ag) Kit
        Positive 3 - 3
        Negative - 5 5
        Total 3 5 8
        Positive Percent Agreement (PPA) 100% (3/3)
        Negative Percent Agreement (NPA) 100% (5/5)
      7. 07

        Precision Optics/Mechatronics Technology

        Development of new medical devices (diagnostic equipment) with precision optics/mechatronics technology

        Core technology(New technology medical device)

        Circulation tumor cell(CTC)Microfluidic chip and separation equipment technology (Flow Cytometric Technology)

        Microfluidic circuit design technology

        CTC separation cartridge design and driving technology

        High-sensitivity precision optical scan image processing technology for cancer cell analysis

        High-precision cell image scanning technology

        Cancer cell image processing and analysis technology

        Liquid biopsy procedure

      8. 08

        Microbial Field Analysis Technology

        Cellular NADH Measurement - Self Fluorescence Measurement

        Microbial autofluorescence detection scanner

        The difference in signal intensity by cell (MDAMB231) concentration

        Microbial autofluorescence detection optical module

      9. 09

        Cell counting technology

        Technology to measure the type and quantity of cells by combining AI technology using precision imaging optical technology

        4 Image stitching